Diabetes & Atherosclerosis

Terri Allen (left) in the Atherosclerosis laboratory
Dr Terri Allen (left) in the Atherosclerosis laboratory

Supervisor: Terri Allen
Email:  terri.allen@bakeridi.edu.au
Phone:  03 8532 1739

Did you know that diabetes is the leading cause of blindness, kidney disease and people with diabetes are much more likely to die of heart disease?

Well now you do. Want to do something about it? Yes, so do we!

We are part of a large division called Diabetic Complications headed by Professor Mark Cooper who is the Chief Scientific Officer here at Baker IDI.

Our laboratory is well-funded from government, National Heart Foundation, pharmaceutical companies and private charities such as the Juvenile Diabetes Research Foundation.

We are well sourced with state of the art equipment, pathology labs, technical assistance and our own group of experienced and very helpful animal technicians.

All the right ingredients for a successful honours project...

What techniques will you learn?

Animal handling, surgery, pathology, immunohistochemistry, realtime RT-PCR, genotyping, tissue culture, computer search skills for literature reviews, statistical analysis, correct use of graphics to name a few.

We have some exciting projects planned that look at new ways to try and treat or prevent the development of atherosclerosis in type 1 diabetes.

We utilise a special mouse model developed here at our institute. We have access to unique early phase molecules from pharmaceutical companies. We also study transgenic and KO mice to look at pathways of disease. We also collaborate with other groups here at the Baker.

The titles of the projects we offer include:

  • The role of Urotensin II in diabetic atherosclerosis.
  • The role of Urotensin II in diabetic kidney disease.